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is anticholinesterase the same as cholinergic agonist?
for treating myastemia gravis would you use a cholinergic agonsit?
2 Answers
- Bob BLv 77 years agoFavourite answer
No. Acetylcholinesterase is the enzyme that breaks down acetylcholine. Its more akin to a cholinergic antagnoist in that respect- it stops acetylcholine.
Now, as for MG, the problem is that the immune system is fighting the acetylcholine receptors. Usually the treatment aims around trying to stop this. Apart from that the main treatment is an acetylcholinesterase inhibitor- this keeps the acetylcholine around for longer to make it more effective.
Cholinergic agonists aren't as good an idea- they don't really behave in the same way as acetylcholine itself and have various side effects that mean they aren't really good drugs. As far as I know they aren't used for MG.
