Need help with disabling Windows autorun files to get rid of "file not found" message for .dll file?

I have spent quite some time now looking at how to get rid of this error message that keeps popping up: "There was a problem starting C:\PROGRA~1\Common~1\System\sysmenu.dll The specified module cannot be found."

What I have read is that it has to do with a virus or malware that left a registry entry after my antispyware uninstalled it. I have been following this thread as a "how to" to try to get rid of the messages: http://answers.microsoft.com/en-us/windows/forum/w...

My problem is that I do not want to be disabling anything I would need. Is it very bad to uncheck an item from autorun if it is needed? Can I recheck it later? Is it normal that I have many unfound files that show up in autorun?

My issue specifically is with whether or not I should uncheck these three: YTDownloader (which I think is the file that installed the very annoying Spigot program) and two other files whose "image path" are the exact sysmenu.dll files I am getting the message for and which both have "SMUpdate2(/3)" in their file names. When I click to uncheck these two, it makes me "run as administrator" to change them, which worries me a little because it then takes me to the "allow this program to make changes to your computer" screen and I do not want to royally mess up my computer over a simple thing. Any advice you could give would be great!!